Norrie disease and peripheral venous insufficiency

Norrie disease and peripheral venous insufficiency

Norrie disease (ND) is a rare X linked recessive disorder in which affected males are blind at birth or in early infancy. About one third develop progressive sensorineural deafness. In addition, about 25% of affected males have varying degrees of developmental delay. The ocular findings include bilateral retinal folds, retinal detachment, vitreous haemorrhage, and bilateral retrolental masses c...

Norrie disease and peripheral venous insufficiency.

frequency of peripheral arterial disease in patients with chronic venous insufficiency

conclusions the peripheral arterial disease is more frequent in patients with the severe form of cvi, than in patients without cvi. concomitant risk factors for cvi and pad were high bmi and hypertension. in each patient with severe cvi it is necessary to determine the abpi, in order to exclude the presence of pad. results our results showed that the risk factors for cvi were high body mass ind...

Novel mutations in Norrie disease gene in Japanese patients with Norrie disease and familial exudative vitreoretinopathy.

PURPOSE To search for mutations in the Norrie disease gene (NDP) in Japanese patients with familial exudative vitreoretinopathy (FEVR) and Norrie disease (ND) and to delineate the mutation-associated clinical features. METHODS Direct sequencing after polymerase chain reaction of all exons of the NDP gene was performed on blood collected from 62 probands (31 familial and 31 simplex) with FEVR,...

Frequency of Peripheral Arterial Disease in Patients With Chronic Venous Insufficiency.

BACKGROUND It is estimated that about 15% (10% - 30% in most of the studies) of the total adult population has some aspects of the Chronic Venous Insufficiency (CVI). Frequency of the Peripheral Arterial Disease (PAD) in the adult population is 3% - 4%. Studies dealing with etiopathogenesis of leg ulcers show that between 10% and 18% of all ulcers are of mixed, arterial-venous origin. OBJECTI...